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Epsilon Health

Software Engineer - ML Infrastructure

San Francisco, CA
Level
Senior
Work type
On-site · San Francisco

Not stated in the posting: salary, visa.

Open. First seen 3 October 2026.

About the role

About Us

Epsilon Health is transforming medical imaging and diagnostics by bringing frontier AI into clinical practice. We're tackling some of healthcare's most critical challenges, building technology that directly improves patient outcomes.

This year, we've served over 300,000 patients and now serve 3,000+ daily, working with some of the largest medical institutions in the U.S. By year-end, we're on track to interpret 1% of all daily U.S. X-rays.

Our research team brings experience from DeepMind and Meta, powered by one of the industry's most comprehensive proprietary medical imaging datasets, continuously enriched by real-world clinical data. Together, we're building a future where frontier AI helps save millions of lives today, not tomorrow.

Recently out of stealth, we're proudly backed by Jack Altman, Uncork Capital, Renegade Partners, and AlleyCorp, one of NYC's most active healthcare venture firms.

Role Overview

We’re looking for an ML infrastructure engineer to design and build the core systems that enable scalable, efficient training of large models for deployment and research. Your goal is to make experimentation and training at Epsilon Health fast and reliable to ensure our research teams can focus on science rather than system bottlenecks.

Sitting in the Engineering team and working closely with research, you'll own the distributed training and reinforcement learning infrastructure our foundation-model and post-training work runs on, and the inference and evaluation systems that carry models from experimentation into production.

Key Responsibilities

  • Partner directly with researchers to deeply understand their workflows, then anticipate and design for how those needs will change
  • Build a distributed training infrastructure for foundation models on large-scale medical imaging, including the long-context parallelism and checkpointing that volumetric CT/MR training demands.
  • Build high-throughput data loading and preprocessing that keeps GPUs saturated on large volumetric and multimodal datasets.
  • Partner with researchers to prototype new ideas and translate them into production-ready code, owning end-to-end delivery from experimentation through deployment and monitoring.
  • Contribute to production serving and deployment pipelines (model rollout, canary deployments, and monitoring) alongside the backend team.
  • Build the reinforcement learning training stack (high-throughput rollout generation, reward-model serving, and experience collection), enabling the research team to run online, multi-reward RL at scale.

Qualifications

  • 6+ years of experience designing, building, and operating large-scale distributed systems or infrastructure in production
  • Have 2+ years of experience building ML infrastructure or systems in production
  • Strong Python skills and expertise in PyTorch or JAX
  • Experience and familiarity with the compute, tooling, and workflow needs of large-scale machine learning research
  • Experience building infrastructure or platforms specifically for research or machine learning workflows
  • Deep experience building and operating Kubernetes and cloud infrastructure at scale
  • Experience with distributed training at scale (FSDP, DeepSpeed, or Megatron-style parallelism) and the systems concerns of keeping large GPU jobs efficient
  • Prior experience as a technical lead or mentor for other engineers

Preferred Qualifications

  • Experience operating in a startup or startup-like environment, i.e. a small, fast-moving team with high autonomy
  • Experience building reinforcement learning training infrastructure: rollout generation, reward-model serving, or online/off-policy learning systems
  • Experience with high-performance inference and serving (vLLM, SGLang, TensorRT, or Triton) for both training-time rollouts and production
  • Experience optimizing inference and serving for large models: batching, KV/prompt caching, quantization, and low-latency, high-throughput sampling.
  • Experience optimizing training performance: parallelism, distributed communication, mixed/low precision, and utilization.
  • Experience building internal training or experimentation platforms used by research teams, supporting A/B testing and experimentation workflows
  • Familiarity with vision-language models (VLMs) or multimodal architectures

The team: Engineering

This role is one of 3 open in Engineering. 3 were posted in the last 30 days.

WHAT THE TEAM WORKS WITH, ACROSS ITS POSTINGS

Machine Learning (2 of 3), Python (2 of 3), React (2 of 3), TypeScript (2 of 3)

OTHER ROLES ON THIS TEAM

From the team and dates on Epsilon Health's own job board.

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