Principal Machine Learning Engineer (Reconstruction / Quantitative Imaging)
San Francisco
- Salary
- $290K - $302K
- Level
- Principal
- Work type
- On-site · San Francisco
Not stated in the posting: visa.
Open. First seen 22 October 2026.
About the role
What you’ll do
- Partner with medical image reconstruction scientists / engineers to build ML components that improve reconstruction quality, speed, robustness, or quantitative accuracy.
- Define training/evaluation pipelines, datasets, and metrics that map to user needs and design requirements.
- Productionize models: inference performance, reproducibility, monitoring for drift/regressions, and safe fallbacks.
- Collaborate on hybrid algorithms, incorporating physics and learned priors, denoisers, learned regularizers, and quality estimation.
- Help build tooling for rapid experimentation as well as rigorous verification of algorithm changes.
What we’re looking for
- Strong applied ML experience plus comfort with signal processing / imaging or adjacent domains.
- Ability to move fluidly between research prototypes and production-quality systems.
- Strong evaluation discipline: metrics, ablations, data leakage avoidance, and reproducibility.
- A demonstrated track record of applying ML to physics-based or inverse problems (i.e., shipped projects, a portfolio, or publications.)
Useful experience
- ML for imaging/inverse problems (or adjacent) with strong evaluation discipline and comfort with GPU performance constraints.
- Pragmatic production mindset: reproducible training/inference, regression testing, and safe deployment in high-stakes contexts.
- A background in computational physics or scientific computing.
- Leverage ML-based methods such as PiNNs and Neural Operators to solve partial differential equations arising in ultrasound simulation and imaging.
- Experience in Agentic-SciML is a plus.
- Hands-on experience with data curation for ML: building datasets from messy, real-world sources, defining ground truth, and managing labeling or simulation pipelines.
- Background in data assimilation: combining observations with physics-based models (Kalman filtering, variational methods, ensemble approaches, or learned variants).
The team: Midjourney Medical
This role is one of 8 open in Midjourney Medical.
WHAT THE TEAM WORKS WITH, ACROSS ITS POSTINGS
Python (3 of 8)
OTHER ROLES ON THIS TEAM
- Physical Scientist / Test Engineer posted Sep 18
- Senior Machine Learning Engineer (Clinical Team) posted Sep 18
- Hardware Physicist posted Sep 7
- Senior Mechanical Engineer (Medical) posted Aug 24
- Principal Electrical Engineer (Design Lead) posted Jul 30
- Senior Cloud / Data Engineer (Data / Reconstruction / HIPAA) posted Jun 30
- Principal Software Engineer posted Jun 30
From the team and dates on Midjourney's own job board.
See Machine Learning Engineer salaries in San Francisco →
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