Lead Platform Engineer
- Salary
- $220,000 - $300,000 annually
- Level
- Lead
- Work type
- On-site · San Francisco
- Visa
- Not offered
Open. First seen 3 November 2026.
About the role
About the Role
Lead the platform engineering effort at an early-stage biotech data infrastructure company. You will own the architecture, security, and scale of a foundational platform that turns diverse laboratory data into a unified, queryable knowledge base for scientists and AI agents.
What You'll Do
- Set the architectural direction and build ingestion pipelines, APIs, microservices, and storage layers for heterogeneous scientific data, preserving data provenance.
- Operate knowledge graphs and vector search systems to support combined symbolic and semantic retrieval.
- Build high-concurrency services in Go and Python, including controlled agent write boundaries and isolated execution environments.
- Define security boundaries, including service authentication, tenant isolation, secrets management, encryption, and zero-trust practices.
- Own cloud infrastructure, CI/CD, observability, SLOs, and internal developer workflows.
- Establish engineering standards, review code, mentor engineers, and help grow the platform team.
- Partner with company leadership on team design and platform engineering recruitment.
What We're Looking For
- At least 5 years of platform or infrastructure engineering experience, with a track record building and operating production backend infrastructure, data platforms, or distributed systems.
- Strong experience with Kubernetes, Terraform, Ansible, and modern CI/CD systems.
- Experience designing ingestion for messy, multi-source data, including schema harmonization and entity resolution.
- Proficiency with Go and Python or FastAPI, plus production data systems such as knowledge graphs or vector search.
- Experience with production security, observability, and infrastructure engineering, in addition to software development.
- Leadership experience setting architecture, mentoring engineers, or establishing engineering rigor; biotech data experience and SOC 2 or similar compliance experience are beneficial.
- Must be authorized to work in the United States without visa sponsorship or transfer.
Compensation & Benefits
Base salary: $220,000 to $300,000 annually. Visa sponsorship is not available.
Location
On-site, five days per week in San Francisco, California. Relocation assistance is available.
What this role asks for
Standard for DevOps / SRE / cloud roles
CI/CD · Kubernetes · Python · Terraform
Common in DevOps / SRE / cloud postings at any company.
Compared with True Talent Solutions Partners's other open jobs.
The team: Client Roles
This role is one of 127 open in Client Roles. 127 were posted in the last 30 days, including 7 lead roles: the team is hiring the people who run it too.
WHAT THE TEAM WORKS WITH, ACROSS ITS POSTINGS
Python (66 of 127), LLM (48 of 127), TypeScript (46 of 127), React (44 of 127), JavaScript (27 of 127), Machine Learning (27 of 127), AWS (25 of 127)
OTHER ROLES ON THIS TEAM
- Senior/Staff Full Stack Engineer posted Nov 3
- Founding Engineer posted Nov 3
- Product Engineer posted Nov 3
- Full-Stack Engineer, Agent Evaluation & Reliability posted Nov 3
- Senior/Staff Product Engineer, Applied AI posted Nov 3
- Senior Control Electronics Engineer posted Nov 3
- Lead Software Engineer, Platform posted Nov 3
- Technical Product Manager posted Nov 3
- Senior Forward Deployed Engineer posted Nov 3
- Research Engineer, Evals posted Nov 3
- Founding Product Engineer posted Nov 3
- Frontend Engineer posted Nov 3
- Fullstack Software Engineer posted Nov 3
- Founding Forward Deployed Engineer posted Nov 3
- Founding AI Engineer posted Nov 3
- Senior Platform Engineer posted Nov 3
- Founding ML Research Engineer posted Nov 3
- Forward Deployed Engineer posted Nov 3
- Member of Technical Staff, Compiler posted Nov 3
- Founding Engineer posted Nov 3
- AI Scheduler posted Nov 3
- Product Engineer, Mid-Senior posted Nov 3
- Product Manager, Supply Chain posted Nov 3
- Founding Full-Stack Engineer posted Nov 3
- Founding Forward Deployed Engineer posted Nov 3
- Product Manager, Product Growth posted Nov 3
- Founding Product Designer posted Nov 3
- Software Engineer, iOS posted Nov 2
- Electrical & Computer Engineer posted Nov 2
- Founding Backend Software Engineer posted Nov 2
- Senior Full Stack Software Engineer posted Nov 2
- Founding AI Agent Engineer posted Nov 2
- Senior Forward Deployed Engineer, Operate posted Nov 2
- Engineering Lead posted Nov 2
- Robotics Software Engineer posted Nov 2
- Product Manager, AI Platform posted Nov 2
- Staff Software Engineer, Infrastructure posted Nov 2
- Senior Software Engineer, Autonomous Systems posted Nov 2
- Agent Deployment Engineer posted Nov 2
- Engineering Manager, Agents posted Nov 2
- Founding Fullstack Engineer posted Nov 2
- Lead Platform Engineer posted Nov 2
- Founding Product Designer posted Nov 2
- Founding PLM Solutions Engineer posted Nov 2
- Forward Deployed Engineer posted Nov 2
- Software Engineer posted Nov 2
- Design Engineer posted Nov 2
- Research Crawling Engineer posted Nov 2
- Senior/Staff Software Engineer posted Nov 2
- Software Engineer, AI Agents posted Nov 2
- Senior Full-Stack Engineer posted Nov 2
- Full-Stack Engineer, AI Agents posted Nov 2
- Senior Power Electronics Engineer posted Nov 2
- Software Engineer, Marketplace posted Nov 2
- Engineering Manager posted Nov 2
- Senior AI/ML Engineer posted Nov 2
- Mechanical Engineer posted Nov 2
- Computer Vision ML / Research Engineer posted Nov 2
- Senior Software Engineer posted Nov 2
- Senior Full Stack Engineer posted Nov 2
- Member of Technical Staff, ML Systems posted Nov 2
- AI-Native Electrical Engineer posted Nov 2
- Mid/Senior Full Stack AI Engineer posted Nov 2
- Forward Deployed Product Manager posted Nov 2
- Director of Engineering posted Nov 2
- Founding Senior Engineer posted Nov 2
- Product Lead posted Nov 2
- Forward Deployed Engineer posted Nov 2
- Senior Backend Software Engineer posted Nov 2
- Staff Product Manager posted Nov 2
- Founding Product Designer posted Nov 2
- Member of Technical Staff, Applied Researcher posted Nov 2
- Senior Security Engineer posted Nov 2
- Senior Solutions Engineer, Digital Native and Mid-Market posted Nov 2
- Product Engineer posted Nov 2
- Software Engineer, C++ Systems posted Nov 2
- Senior Software Engineer posted Nov 2
- Member of Technical Staff, AI Agents posted Nov 2
- Lead Product Engineer posted Nov 1
- Engineering Manager posted Nov 1
- Member of Technical Staff posted Nov 1
- Technical Recruiter posted Nov 1
- Product Manager, AI Education posted Nov 1
- Agent Deployment Engineer posted Nov 1
- Full Stack Engineer posted Nov 1
- Forward Deployed Engineer posted Nov 1
- Brand & Identity / Presentation Designer posted Nov 1
- Senior Full-Stack Software Engineer posted Nov 1
- Founding Engineer posted Nov 1
- Full-Stack Product Engineer posted Nov 1
- Senior ML / AI Engineer posted Nov 1
- Senior LATAM Brazil QA Engineer posted Nov 1
- Senior Full-Stack Engineer posted Nov 1
- Director of Engineering posted Nov 1
- GTM Engineer posted Nov 1
- Forward Deployed Engineer posted Nov 1
- Senior / Staff Product Engineer posted Nov 1
- Member of Technical Staff posted Nov 1
- Senior Analog/Mixed Signal Engineer posted Nov 1
- Forward Deployed Product Manager posted Nov 1
- Software Engineer, Distributed Systems (Core) posted Nov 1
- Founding Engineer posted Nov 1
- Member of Technical Staff posted Nov 1
- Product Engineer, Scrape posted Nov 1
- Solutions Engineer posted Nov 1
- Principal Software Engineer, Perception posted Nov 1
- Backend Infrastructure Engineer, Anti-Bot posted Nov 1
- Principal Analog/Mixed-Signal Engineer posted Oct 31
- Senior Member of Technical Staff, Platform posted Oct 31
- Robotics Infrastructure Engineer posted Oct 31
- Staff Product Manager, AI posted Oct 31
- Member of Technical Staff, Research Engineering posted Oct 31
- Founding Product Engineer posted Oct 31
- Head of RF Engineering posted Oct 31
- Software Engineer, Security posted Oct 31
- Senior Software Engineer, Customer Studio Backend posted Oct 31
- Technical Product Manager posted Oct 31
- Founding Software Engineer posted Oct 31
- Electrical Engineer posted Oct 31
- Founding Engineer posted Oct 30
- Data Engineer, Data Product posted Oct 30
- Senior Product Manager, Staffing and AI Agents posted Oct 30
- Founding Product Engineer posted Oct 30
- Software Engineer posted Oct 30
- Senior Software Engineer, Design posted Oct 30
- Member of Technical Staff, Full Stack posted Oct 30
From the team and dates on True Talent Solutions Partners's own job board.
Posting history
Reposted 3 times since 27 October 2026: a posting for this role in San Francisco was taken down and the role was posted again.
- 3 November 2026 – open (this posting)
- 1 November 2026 – closed 3 November 2026
- 31 October 2026 – closed 1 November 2026
- 29 October 2026 – closed 31 October 2026
- 27 October 2026 – closed 29 October 2026
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