Lead Platform Engineer
- Salary
- $205,000 - $235,000 annually
- Level
- Lead
- Work type
- On-site · South San Francisco
- Visa
- Sponsors visas
Open. First seen 28 October 2026.
About the role
About the Role
Lead the compute, data, AI, and security infrastructure behind a biotechnology sequencing operation. You will work across software and lab systems to build reliable platforms that support sequencing workflows and scientific analysis.
What You'll Do
- Own services that orchestrate lab devices, including robots, sequencers, and on-premises Linux servers, along with the data ingestion pipeline.
- Build cloud infrastructure and data pipelines to store, process, and deliver large volumes of sequencing data.
- Design systems for orchestrating large numbers of bioinformatics tasks, including queues, workflow orchestration, and scheduling.
- Develop AI infrastructure and internal tools for operational monitoring, logistics coordination, and adaptive bioinformatics analysis.
- Lead cross-functional projects from problem definition through production, and mentor engineers while contributing as an individual contributor.
What We're Looking For
- At least 5 years of experience in platform, backend, or infrastructure engineering, including meaningful experience at a startup during a period of growth.
- Strong AWS orchestration experience, including ECS, Batch, and Step Functions, plus Python backend development with FastAPI or Django.
- Experience designing and shipping reliable distributed systems, such as task queues, workflow orchestration, and state machines.
- Hands-on experience with Linux server administration and distributed task queues such as Celery or SQS.
- Experience leading cross-functional projects, mentoring engineers, and connecting architecture choices to business impact.
- Familiarity with current AI tooling and experience building LLM or agent systems, including tools, evaluation, permissions, and workflow design.
- A degree in computer science, engineering, mathematics, physics, or equivalent technical experience, along with curiosity about science and biotechnology.
- Comfort working primarily as an individual contributor and operating in an ambiguous, fast-moving environment.
Compensation & Benefits
Base salary is $205,000 to $235,000 annually. Visa sponsorship is available.
Location
Hybrid role based in South San Francisco, California.
What this role asks for
Particular to this role
Celery · Django · FastAPI
Rare in True Talent Solutions Partners's other 59 open postings.
Standard for DevOps / SRE / cloud roles
AWS · Linux · Python
Common in DevOps / SRE / cloud postings at any company.
Compared with True Talent Solutions Partners's other open jobs.
The team: Client Roles
This role is one of 105 open in Client Roles. 105 were posted in the last 30 days, including 5 lead roles: the team is hiring the people who run it too.
WHAT THE TEAM WORKS WITH, ACROSS ITS POSTINGS
Python (56 of 105), TypeScript (43 of 105), LLM (37 of 105), React (37 of 105), Machine Learning (24 of 105), JavaScript (23 of 105), AWS (22 of 105)
OTHER ROLES ON THIS TEAM
- Product Manager, Product Growth posted Oct 28
- Product Manager, AI Platform posted Oct 28
- Machine Learning Engineer posted Oct 28
- Forward Deployed Engineer posted Oct 28
- Senior Solutions Engineer, Digital Native and Mid-Market posted Oct 28
- Founding Product Engineer posted Oct 28
- Senior Product Manager posted Oct 28
- Mechanical Design Engineer posted Oct 28
- Member of Technical Staff, Agent Platform posted Oct 28
- Senior Security Engineer posted Oct 28
- Software Engineer, Infrastructure posted Oct 28
- Senior Software Engineer, Core Systems posted Oct 28
- Forward Deployed Software Engineer, Tactical Edge posted Oct 28
- Senior/Staff Software Engineer posted Oct 28
- Software Engineer, RL Environments posted Oct 28
- Founding Backend & Infrastructure Engineer posted Oct 28
- Solutions Engineer posted Oct 28
- Product Engineer, Scraping posted Oct 28
- Senior Software Engineer, Customer Studio Backend posted Oct 28
- Founding Reinforcement Learning Engineer posted Oct 28
- Senior Quantitative Developer posted Oct 28
- Principal Analog/Mixed Signal Engineer posted Oct 28
- Senior Software Engineer posted Oct 28
- Engineering Manager posted Oct 28
- Member of Technical Staff posted Oct 28
- Founding Product Engineer posted Oct 28
- Fullstack Software Engineer posted Oct 28
- Founding ML Researcher posted Oct 28
- Founding Forward Deployed Engineer posted Oct 28
- Frontend Engineer posted Oct 28
- Founding Forward Deployed Engineer posted Oct 28
- Software Engineer, iOS posted Oct 28
- Forward Deployed AI Engineer posted Oct 28
- Senior Platform Engineer posted Oct 28
- Founding Engineer posted Oct 28
- Software Engineer (Full Stack) posted Oct 28
- Founding Full-Stack Engineer posted Oct 28
- Senior Forward Deployed Engineer, Operate posted Oct 28
- Product Manager, Supply Chain posted Oct 28
- Forward Deployed Engineer posted Oct 28
- Founding Full-Stack Engineer posted Oct 28
- Founding AI Engineer posted Oct 28
- Senior Full Stack Software Engineer posted Oct 28
- Product Engineer, Mid-Senior posted Oct 28
- Founding Engineer posted Oct 28
- Member of Technical Staff, Compiler posted Oct 28
- AI Scheduler posted Oct 28
- Mid/Senior Full Stack AI Engineer posted Oct 28
- Founding Backend Software Engineer posted Oct 28
- Director of Engineering posted Oct 28
- Founding Senior Engineer posted Oct 28
- Senior Engineering Manager posted Oct 28
- Full-Stack Software Engineer posted Oct 28
- Software Engineer, Security posted Oct 28
- Founding Product Designer posted Oct 28
- Software Engineer, Edge AI Systems posted Oct 28
- Senior Software Engineer, Distributed Systems (Core) posted Oct 28
- Product Engineer posted Oct 28
- Agent Deployment Engineer posted Oct 28
- Backend Software Engineer posted Oct 28
- Technical Product Manager posted Oct 28
- Engineering Manager, Agents posted Oct 28
- Security Lead posted Oct 28
- Founding Fullstack Engineer posted Oct 28
- Software Engineer posted Oct 28
- Senior/Staff Product Engineer, Applied AI posted Oct 28
- Lead Software Engineer, Platform posted Oct 28
- Applied AI Engineer posted Oct 28
- Software Engineer posted Oct 28
- Senior Control Electronics Engineer posted Oct 28
- Founding Member of Technical Staff, Markets posted Oct 28
- Founding AI Agent Engineer posted Oct 28
- Senior / Staff Software Engineer, Infrastructure posted Oct 28
- Founding Forward Deployed Engineer posted Oct 28
- Electrical & Computer Engineer posted Oct 28
- Founding Product Designer posted Oct 28
- Data Engineer, Data Product posted Oct 27
- Member of Technical Staff, Full Stack posted Oct 27
- Electrical Engineer posted Oct 27
- Software Engineer posted Oct 27
- Founding Forward Deployed Engineer posted Oct 27
- Lead Platform Engineer posted Oct 27
- Staff Product Manager posted Oct 27
- Founding PLM Solutions Engineer posted Oct 27
- Backend Infrastructure Engineer, Anti-Bot posted Oct 27
- Principal Software Engineer, Perception posted Oct 27
- Senior Software Engineer, Design posted Oct 27
- Founding Software Engineer posted Oct 27
- Forward Deployed Engineer posted Oct 27
- Software Engineer posted Oct 27
- Technical Product Manager posted Oct 27
- Design Engineer posted Oct 27
- Chief Product Officer posted Oct 27
- Research Crawling Engineer posted Oct 27
- Forward Deployed Engineer, Infrastructure posted Oct 27
- Lead Product Engineer posted Oct 27
- Member of Technical Staff, ML Systems posted Oct 27
- Product Lead posted Oct 27
- Engineering Lead posted Oct 27
- Forward Deployed Product Manager posted Oct 27
- Senior/Staff Software Engineer posted Oct 27
- Senior Full-Stack Engineer posted Oct 24
- Software Engineer, AI Agents posted Oct 24
- Full-Stack Engineer posted Oct 23
From the team and dates on True Talent Solutions Partners's own job board.
Salary context
5 other open postings titled Lead Platform Engineer state a salary: median USD 205,000 to USD 249,000 a year.
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